- Best slayer build core: Blood Manipulation evil art paired with sickles for multi-hit damage
- Weapon path: Regular Sickles, then Blood Sickles, Damascus, and Nightfall Sickles
- Fighting style: Soryu (level 62, demon-only) for counter openings
- Best clan: Koamd for sun immunity, healing, and damage combined
- Boss rotation: C → dash → V → dash → B → dash → reposition, then repeat
Best Slayer Build Overview: The Blood Demon Setup
The best slayer build in Slayer 2 for farming bosses, pushing dungeons, and leveling mastery is a full-damage demon setup built around Blood Manipulation. Most of its abilities hit enemies multiple times, so flat additional damage gear and sickle weapon stats compound into massive sustained damage. You can keep attacking while weapon skills are on cooldown, making the rotation feel faster than one-or-two-move builds.
Video Highlights:
- Blood Manipulation rolls/purchases from Muzan's domain after becoming a demon
- Full sickle progression from Regular to Nightfall tier 3
- Soryu trial walkthrough with all four objectives
- Recommended duelist gear, clans, and titles for max damage
You cannot use Blood Manipulation without sickles equipped. Weapon progression is not optional in this build — it is the foundation of your damage.
Weapon Progression: Sickle Upgrade Path
Your sickles stay equipped while using your evil art, so their additional damage directly boosts blood attacks. Follow this upgrade path in order:
| Weapon | How to Obtain | Key Stats |
|---|---|---|
| Regular Sickles | 15% drop from Huzo (Ice Valley cave behind waterfall) | +1 dmg, 1.0x dmg factor, block points |
| Blood Sickles | 7% drop from Gutai (right of Windy Peak, near shrine) | +2 dmg, 1.04x factor, +2.25 block |
| Damascus Sickles | Crafted at Aokigahara | +4 dmg, 1.08x factor, +5.1 block, 1.9x block regain |
| Nightfall Sickles | Craft with Damascus + materials after all 10 Nightfall levers | +5.75 dmg, 1.15x factor, +7.95 block, 2.31x block regain, +5 stamina |
While farming Huzo, also get Sither Vortex (second sickle skill). While farming Gutai, get Circular Slashes — it unlocks the final Blood Manipulation ability. Leaving with only the weapon makes later farming much harder.
Nightfall items can be upgraded to Tier 2 and Tier 3 using Nightfall Forge Ingots and Nightfall Reinforced Plating. Both drop from Aokigahara chests (5%) or world event chests (2%). Never sell or waste these materials — they are required for the endgame version of the build.
Farm Huzo for Regular Sickles + Sither Vortex
Find Huzo in the cave behind the waterfall at the lower edge of Ice Valley. Do not leave without both drops.
Farm Gutai for Blood Sickles + Circular Slashes
Gutai is right of Windy Peak, below and right of the shrine. These two upgrades unlock your full rotation.
Craft Damascus Sickles
Craft at Aokigahara. This carries you through most mid and late-game farming.
Activate all 10 Nightfall levers
Must be done in the same server. Collect the Nightfall Sickles schematic, then craft using your Damascus Sickles and materials.
Upgrade to Tier 2 and Tier 3
Save Nightfall Forge Ingots and Reinforced Plating from chests to finish the endgame weapon.
Do not dump refinement materials into Regular or Blood Sickles if you are close to replacing them. Save most materials for Damascus and Nightfall Sickles. Use a refinement guard to prevent a bad result from downgrading your weapon.
Becoming a Demon and Unlocking Blood Manipulation
Lower your reputation
Reputation must drop before you can begin the demon transformation questline.
Complete Muzan's questline
Finish the full quest line to become a demon.
Return to Muzan's domain
Use your bell after transforming to travel back.
Roll or purchase an evil art
Keep rolling until you obtain Blood Manipulation, then use its item and complete the training questline to unlock the art.
It is one of the strongest PvE evil arts because most abilities hit multiple times. A boss staying inside the full attack loses a huge amount of health, and repeated hits scale directly with your flat damage gear.
Soryu Fighting Style: The Four Objectives
Soryu is exclusive to demons, requires level 62, and needs fishing unlocked. Kazuma stands near the small bridge and house northeast of the bare area, past Shobu.
| Objective | Requirement | Location / Tip |
|---|---|---|
| Fish Delivery | Catch and hand in 20 common fish | Only common rarity counts — rare catches do not progress |
| Soryu Scroll | Collect from the flooded cave | Swim in near the waterfall, search near the wheel at the back |
| Basic Damage | Deal 8,000 basic attack damage with fists | Use enemies you can defeat consistently |
| Defeat Goki | Beat Soryu Trainee Goki | Cave hidden by the nearby waterfall; bait his counters, punish after |
Goki can counter. Do not mindlessly attack while he waits — bait out his response, block or move away, then punish him when he finishes.
The main reward is Bone Breaker, a counter that knocks enemies down and creates openings for blood and sickle skills. Face Breaker rushes, grabs, and slams enemies into the ground. Farm the trainee and raise Soryu mastery to unlock these.
Equipment, Clan, and Titles
For a full damage setup, use duelist gear with flat additional damage, because Blood Manipulation's repeated hits multiply every point.
| Equipment Piece | Source | Drop Rate | Stats |
|---|---|---|---|
| Stone Hawery | Gure | 3% | +2 dmg, 1.02x factor, 100 HP, 80 stamina |
| Bamboo Muzzle | Nezuro | 3% | +2 dmg, 1.01x factor, 105 HP, 80 stamina |
| Demonic Lantern | World event chests | 3% | +2 dmg, 1.01x factor, 70 HP, 55 stamina, night light |
| Nightfall Mask | Crafted at Allen | Craft | +2 dmg, 1.01x factor, 90 HP, 58 stamina |
| Fifth damage piece | Aokigahara chests | 5% | Demonic Horns 2, Silver Fang Mask, Red Oni Mask, or Kieran Lantern |
World Boss Setup
- Full flat damage gear
- Kill bosses before they attack
- Maximum farming speed
Dungeon Setup
- Swap 1-2 pieces to survival
- Black Dragon Armor or First Light gear
- Prioritize health regain and damage reduction
Daytime Sun Protection
- Flame Amigasa (+1.06x dmg factor, sun immunity)
- Koamd clan gives full sun immunity
- Classic straw hat only as a last resort
| Clan | Key Bonuses | Best For |
|---|---|---|
| Koamd | 175 HP, 23% dmg factor, 130 stamina, damage reduction, sun immunity, Regain Adrenal (+14% HP regain 7s), Combat Intuition | Best all-around pick |
| Rengoku | 26% additional damage factor, Heartblaze mode +18% while active | Pure damage |
| Uzui | 21% dmg factor, Enhanced Hearing marks enemies for +25% damage taken, 10s | Mark-and-burst damage |
Recommended titles: Annihilator (10M total damage, +2 dmg), Reaper (15,000 enemies defeated, 1.02x dmg factor), and Blood Manipulation Perfected (max mastery, 1.02x evil art damage factor). While progressing, use Demon, Hard Hitter, Bone Breaker, Devastator, Blooded, or Monster Hunter as available stepping stones.
Start with any gear that gives additional damage or damage factor. Blood Manipulation, Regular Sickles, and Soryu improve your farming far more than hours spent hunting one perfect accessory early on.
Boss Rotation and Skill Tree
The rotation is what makes this the best slayer build for bossing. Dash toward the enemy after every skill to maintain pressure and stay in range.
Full rotation order: C → dash → V → dash → B (ultimate) → dash → N (reposition into a wall or corner) → dash → repeat C and V as they come off cooldown.
With Blood Manipulation and sickles giving eight skills total, you can chain attacks without letting the boss recover. If it survives the full rotation, switch to Soryu, counter its next attack with Bone Breaker, then switch back and continue.
Skill tree priorities:
| Priority | Nodes | Reason |
|---|---|---|
| High | Additional damage | Scales every multi-hit attack |
| High | Max health, health regain speed | Survive mistakes; essential for dungeons |
| High | Stamina, stamina regain speed | Complete your full rotation without running dry |
| Medium | Max stamina thresholds | Enough to dash and defend throughout fights |
| Low | Block upgrades | Less important for max damage, but still block dangerous hits |
Take Muzan quests whenever they match the bosses you plan to farm for bonus XP, cash, and mastery. Quest rewards scale with how many high-level demons are in your server, so rewards vary between servers.
Endgame Build Checklist:
- Unlock Blood Manipulation and reach max mastery
- Craft Nightfall Sickles and Nightfall Mask
- Upgrade Nightfall items to Tier 3
- Complete Soryu trial and unlock Bone Breaker
- Equip a full flat-damage duelist set
- Join the Koamd clan and equip Annihilator, Reaper, and Blood Manipulation Perfected titles
FAQ
Q: What is the best slayer build in Slayer 2 for boss farming?
Blood Manipulation with Nightfall Sickles, Soryu, Koamd clan, flat-damage duelist gear, and the Annihilator, Reaper, and Blood Manipulation Perfected titles. The multi-hit evil art combined with flat damage stats melts bosses before they can respond.
Q: How do I get Blood Manipulation in Slayer 2?
Lower your reputation, complete Muzan's questline to become a demon, then use your bell to return to Muzan's domain. Roll or purchase the Blood Manipulation evil art, use its item, and finish the training questline.
Q: Why do sickles matter for a Blood Manipulation build?
Sickles stay equipped while using your evil art, so their additional damage and damage factor boost your blood attacks. Blood Manipulation also cannot be used properly without sickles equipped.
Q: Is Koamd the best clan for this build?
Koamd is the best all-around choice because it combines damage, healing, stamina, defense, and full sun immunity. If you only want maximum damage, Rengoku and Uzui are also strong alternatives.